Thiol redox biochemistry: insights from computer simulations
نویسندگان
چکیده
منابع مشابه
Cytoskeletal mechanics of neurulation: insights obtained from computer simulations.
The morphogenetic movements associated with the process of neurulation have been the subject of much investigation during the last one hundred years. A plethora of experimental evidence has been generated regarding the forces that drive this seemingly simple process, and many theories about the mechanics of the process have been proposed. Recent computer simulations have proved useful for evalu...
متن کاملCan We Trust the Transgenic Mouse? Insights from Computer Simulations
Over the past several decades, the mouse has gained prominence in the cardiac electrophysiology literature as the animal model of choice. Using computer models of the mouse and human ECG, this paper is a step toward understandingwhen themouse succeeds and fails tomimic functional changes resulting from disease states and drug interactions.
متن کاملInteractive computer simulations of genetics, biochemistry, and molecular biology.
This article describes three interactive software simulations targeted to key domains of modern molecular genetics: genetics, biochemistry, and molecular biology. These simulations allow students to deepen their understanding of key principles in these domains by setting up crosses, designing proteins, and designing genes; the simulations then apply these principles to produce results that the ...
متن کاملThe Golgi apparatus: insights from lipid biochemistry.
Discovered by Camillo Golgi in 1898 [ l , 21, the Golgi apparatus has long fascinated cytologists because of its distinct morphology (Fig. 1). This organelle, which is found in all eukaryotic cells, consists of flat cisternae arranged in parallel to form the characteristic ‘stacks’ that are interconnected by cisternal or tubular-reticular bridges. In addition, numerous small membranous vesicles...
متن کاملRedox biochemistry of hydrogen sulfide.
H(2)S, the most recently discovered gasotransmitter, might in fact be the evolutionary matriarch of this family, being both ancient and highly reduced. Disruption of gamma-cystathionase in mice leads to cardiovascular dysfunction and marked hypertension, suggesting a key role for this enzyme in H(2)S production in the vasculature. However, patients with inherited deficiency in gamma-cystathiona...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Reviews
سال: 2014
ISSN: 1867-2450,1867-2469
DOI: 10.1007/s12551-013-0127-x